Ischemic Stroke

Ischemic stroke results from obstruction of cerebral arteries leading to reduced perfusion and oxygen deprivation. Pathophysiology involves thrombus formation, embolic occlusion, cellular energy failure, and excitotoxicity-induced neuronal death. Management strategies focus on clot dissolution, vascular recanalization, antithrombotic therapy, and prevention of recurrent cerebrovascular events. Ongoing research explores neuroprotective compounds, advanced perfusion imaging, and molecular targets that mitigate ischemic cascade damage. Understanding vascular risk factors and endothelial dysfunction remains central to long-term prevention.

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