Neurophysiology and Neurodegeneration

Neurophysiology investigates how the nervous system functions at multiple levels from cellular mechanisms to complex neural networks. Understanding the electrical impulses generated and propagated by neurons is fundamental to comprehending normal brain activity and diagnosing neurological disorders. This discipline encompasses the study of the central and peripheral nervous systems, focusing on functions such as cognition, sensation, and motor control.
 
Neurodegeneration, on the other hand, refers to the progressive loss of neuronal structure and function, leading to debilitating neurodegenerative diseases like Alzheimer’s, Parkinson’s, Huntington’s disease, amyotrophic lateral sclerosis (ALS), and Lewy body dementia. These disorders share common features such as cell death, protein misfolding, and synaptic dysfunction, which gradually impair brain function, memory, and mobility.
 
Research in neurophysiology and neurodegeneration aims to uncover the underlying mechanisms of nerve cell death and network failure. Advanced imaging techniques, including functional MRI and PET scans, enable visualization of brain activity and degeneration patterns in vivo, facilitating early diagnosis and targeted therapies. Studying neuroplasticity the brain's ability to reorganize and repair itself—offers hope for rehabilitative strategies that harness the brain's innate capacity for recovery.
 
This session will explore recent advances in understanding nervous system function, insights into disease pathways, and innovative treatments aimed at halting or reversing neurodegeneration. It emphasizes the importance of integrating neurophysiological research with clinical application toward improving patient outcomes.

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