Scientific Program

Conference Series LLC Ltd invites all the participants across the globe to attend 29th World Congress on Neurology and Therapeutics London, UK.

Day 1 :

Neurology 2020 International Conference Keynote Speaker MAS Ahmed, photo
Biography:

MAS Ahmed is a Clinician with expertise in Childhood Headache. He delivers regular childhood headache clinics at the Queen’s University Hospital, Essex. He is an honorary Senior Clinical Lecturer at Queen Mary University London. His clinical research has focused upon the assessment of patients with emphasis on the use of brain imaging for the well-being of children with headache and visual aura among patients with paroxysmal disorders such as migraine and syncope. He is active in teaching of medical students and paediatricians. He has received top teacher of the year awards and excellence in medical education award by eminent London Universities.

Abstract:

Background: There is a considerable variation in symptoms of Visual Aura (VA) that occur in individuals who fulfil the ICHD criteria of migraine VA. The precise mechanism of migraine VA is not well defined, although its symptoms are generated somewhere in the visual system rather than the eye. Vision is mapped on a variety of cortical areas and each is likely to be specialised for a different visual attribute. Serotonin and acetylcholine are concentrated in Visual Cortex (VC) and Visual Thalamic Neurons (TN), suggesting the role of cholinergic-serotonergic interaction in VA. Neurons of the Retino-Geniculo- Calcarine (RGC) pathway are excitatory to those in the primary VC, while interneurons in the LGN are inhibitory. The RGC visual pathway is also modulated by other factors. Cortical Spreading Depression (CSD) is thought to be the substrate of the migraine aura but could be associated with epileptic seizure. The distance, to which CSD spreads, rests on the steadiness between factors that predispose or inhibit the brain to CSD. The CSD markedly alters neuronal firing of ipsilateral third order thalamic nuclei. The thalamus processes signals from the retina to create images and plays key role in coordinating complex sensory and motor input to and from the cortex.
 
Purpose: To examine the characteristics of migraine VA and to compare its symptoms with that caused by other paroxysmal disorders (e.g. syncope and epilepsy).
 
Method: A qualitative analysis of prospectively collected data, on characteristics of visual symptoms during attacks of migraine and syncope. Diagnosis of migraine VA was based on the ICHD-3 beta. We provide opportunity for patients to illustrate their visual aura symptoms to aid in diagnosis.
 
Results: Visual symptoms were reported by 387/1079 (36%) of migraineurs. 172 (16%) patients fulfilled the ICHD Criteria A, B, C iv and D but missed one (43.5%) or two (56.5%) of the remaining items of criteria C as the visual symptoms were of non-gradual spread (20%), appeared in both visual fields (58%), or lasted less than 5 minutes or more than 60 minutes (75%).
 
Conclusion: Symptoms of migraine VA varied considerably in duration, pattern, mobility, location, mode of onset and colours. Our findings and literature review support the heterogeneity of migraine VA and its overlapping with that of other paroxysmal disorders.
 
Recent Publications:
• Floery D et al. AJNR Am J Neuroradiol. 2012; 33:1546–1552.
• Iizuka T et al. J Neurol Neurosurg Psychiatry. 2015; 86:344–353.
• Vincent MB et al. Cephalalgia. 2007; 27: 1368–1377.
• Rasmussen BK et al. Cephalalgia. 1992; 12: 221-8

 

Neurology 2020 International Conference Keynote Speaker Cheung Chun Luke photo
Biography:

Cheung Chun Luke is the president of Eaulier (Dalian) Hospital. He has invented the micro-current electronic acupoint stimulation therapy, which combines the meridian theory of traditional Chinese medicine and the wavelength theory of Western medicine. This therapy has been applied in treating various illness. The success in Parkinson’s disease has been accepted for publishing in a Chinese Journal (Doctor on-line Medical Journal). Other papers that using this method to treat Parkinson’s disease has been published in a Chinese national outstanding technology journal in 2016/09 and Health and Environment Conference Proceedings 2017 organized by
Hamdan Bin Mohammed Smart University in Dubai.

Abstract:

To investigate the therapeutic effect of micro-current electronic acupoint stimulation therapy on patients with Parkinson's disease. Subjects were 77 hospitalized patients with Parkinson's disease. 57 of them had received prior treatment without further improvement. This new therapy involved stimulating the acupuncture points with micro-current every day for 90 days. With the guide of the therapist, patients used the equipment by themselves to stimulate the related acupuncture points on the sole and body. And the therapist conducted the micro-current therapy on the head through massage. Modified Webster scale was used to analyze effectiveness of treatment. Combining the 10 symptoms, 35 patients (45.45%) had an improvement of more than or equal to 50%, and 19 patients (24.68%) had an improvement between 30% and 50%. Only 14 people (18.18%) improved less than 30%. Each symptom of the patients had significant improvement. This study has shown that micro-current electronic acupoint stimulation therapy can effectively improve the symptoms of Parkinson's disease, which is worthy of clinical promotion and further research.

Neurology 2020 International Conference Keynote Speaker JPN Mishra photo
Biography:

J P N Mishra has his basic expertise in Life Science with specialization in Human Physiology. His previous dimensions of research included
the discipline of Neurobiology, Sleep Medicine and Yogic sciences. He has explored the mechanism of operation in Circadian rhythm and sleep quality following yoga practices. His area of research also includes applied efficacy of different natural phytochemicals on various
carcinoma cells.

Abstract:

Statement of the Problem: The system of Preksha Meditation (PM) is originated from Jain Canonical literature which is based on “Perception of Thoughts”. It is imbued with spiritual powers that cleanse the mind and body of negative energy and thereby facilitate the improvement in various sensory and motor functions of brain, reduces level of stress and enhances the sleep quality and level of
consciousness.
 
Aims: The purpose of this study was to assess the efficacy of PM on adolescent post-graduate students by measuring parameters related to psychological status, neurological functions, sleep quality and
level of consciousness.
 
Methodology: Four components of PM were applied on 50 adolescents. The assessment parameters viz. alpha brain waves, sleep duration, component of REM and Non-REM, Sleep spindles; awareness subjectivity and state of awareness; neurotic reactions, anxiety level, mental ability, fear and emotional level were applied.
 
Findings: The experimental participant students exhibited significantly enhanced number of alpha brain wave omission and reduced level of stress hormones in blood, which led them to remain in state of relaxation. Total Non-REM duration of sleep was found increased with significantly improved sleep quality too, with greater awareness. They were having reduced fear, frustration and anxiety level and emotionally well balanced.
 
Conclusion with Significance: Synchronization of brain waves with alpha waves predominating may be correlated with deep relaxation associated with better sleep quality and improved psychological
state. Positive changes recorded may be attributed to decreased sympathetic activity and parasympathetic dominance, modulated by cortical functions in Central Nervous System. Findings of the study provided a viable and composite programme for health and well-being in adolescents.
 
Recent Publications:
 
• Singh A and Srinivasan N (2019) Concentrative (Sahaj Samadhi) meditation expands subjective time. PsyCh J 8(1):28-35.
 
• Deepak KK (2019) Meditation induces physical relaxation and enhances cognition: A perplexing paradox. Progress in Brain Research 244:85-99.
 
• Parker S (2019) Training attention for conscious non-REM sleep: The yogic practice of yoganidrā and its implications for neuroscience research. Progress in Brain Research 244:255-
272.
 
• Raffone A, Marzetti L Del Gratta C2, Perrucci MG, Romani GL and Pizzella V (2019) Toward a brain theory of meditation. Prog Brain Res. 244:207-232.
 
• Balaji PA, Varne SR and Ali SS (2012) Physiological effects of yogic practices and transcendental meditation in health and disease. North American Jounals of Medical Sciences 4(10):442-448.
 

Keynote Forum

Prabhaker Mishra

Sanjay Gandhi Postgraduate Institute of Medical Sciences, India

Keynote: The importance of sample size in research studies

Time : 10:40-11:10

Neurology 2020 International Conference Keynote Speaker Prabhaker Mishra photo
Biography:

Prabhaker Mishra (DOB: January 1979), presently working as Associate Professor in SGPGI Lucknow-India. He had completed his PhD in Statistics on the topic “Statistical Study of Human vulnerability and Risk. Assessment of Natural Hazards in Orissa” as Senior research fellowship (ICMR) in 2010. He had worked as Assistant Professor (Biostatistics) in the Department of Community Medicine, in medical colleges during 2011 to 2014. He had co-supervised 12 MD students; and presently other 31 MD /2PhD and 1PhD students are pursuing under his co-supervision /supervision. He had published 82 research papers in various national / international journals. His expertise area is applied and medical statistics.

Abstract:

The increasing volume of research by the medical community are also leading numbers of contradictory findings and conclusions. The main reason of the these contradiction are sampling variability and sample size. The differences observed between the groups may represent true difference, but significance level of the same difference is varying from one study to another study due to variation in sample size. Sample size not only affect the level of significance but also affect the power of the study and margin of error. Sample size has no direct relationship with effect size although increasing sample size increases reliability of the effect size detected between the groups. An appropriate sample size, allows the researcher to control the error (Type I & II error). At the time of planning of the study, the researcher must establish a justifiable level of statistical significance, with corresponding power of the study, targeted difference (i.e. effect size) and the variability of the data (for continuous data). The proper planning of sample size can boost the study importance. The aim of this study is to discuss the effect of sample size on level of significance, power of the study and the reliability of the research findings.

Break: Network & Refreshment Break 11:10-11:30 @ Foyer

Keynote Forum

Abhiruchi Galhotra

All India Institute of Medical Sciences, India

Keynote: An overview of health care system in India

Time : 11:30-12:00

Neurology 2020 International Conference Keynote Speaker Abhiruchi Galhotra photo
Biography:

Abhiruchi Galhotra working as Additional Professor, Dept of Community & Family Medicine, AIIMS, Raipur. Nodal Officer for ICMR funded Research Project on Prevalence & Etiology of Hearing Impairment. Post PG teaching experience of 17 years. Supervisor for 2 PG thesis. Contributed 5 chapters in various textbooks of which one is by Springer Nature and 2 others are by Springer. I also have more than 25 research publications to my credit which includes, original articles, review articles, commentary, viewpoint and letter to editor. She has been instrumental in establishing the department of Community & Family Medicine at AIIMS Raipur.

Abstract:

Health Care embraces a multitude of “services provided to individuals or communities by agents of the health services or professions, for the purpose of promoting, maintaining, monitoring,
or restoring health.” Health services meet the needs of entire population; cover the full range of Preventive, Curative and Rehabilitative services, as part of the basic social services of a country. India has a population of over 1.2 billion with 28 states and 9 Union Territories. Central government formulates comprehensive health policies and plans under the direction of the Ministry of Health and Family Welfare for items of national importance, including disease control, medical education, the medical profession and state budgets, are the shared responsibility of the central government and individual states. Public health sector consist of Primary Health Care (Provided at Sub centre), Secondary Health Care (Provided at PHC, CHC, DH) Tertiary Health Care (Provided at large hospitals) Public health sector is multifaceted various types of providers practicing in different systems of medicine, within different ownership structures. Individual states are given primary authority over most aspects of healthcare. An estimated 80% of public healthcare funding comes from the states. In-patient hospitalisation expenditure in India increased to 300% in last 10 yrs in which more than 80% of expenditure met by OOPE, which leads to nearly 6 million families getting into poverty due to catastrophic health expenditure. This led Government of India to launch Ayushman Bharat on 23 September 2018 with objective to cover over 10.74 crore poor and vulnerable families.